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Interestingly, people with pernicious anemia are more likely also to have other autoimmune disorders like type 1 diabetes, autoimmune thyroid disease, and a skin condition called vitiligo

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Neurological Symptoms: It is a common skin problem caused due to vitamin B6 deficiency

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Intriguingly, another interesting research lead to the discovery of a differential role for IRSs in apoptosis, suggesting an antiapoptotic effect for IRS-2 [122] which is consistent with known differential roles of IGF-1 and insulin

What they do not have is a body of controlled evidence showing that injecting them causes clinically significant weight loss independent of diet, exercise, and the rest of a supervised program